NOBS toothpaste was named the 2026 Best Fluoride-Free Toothpaste by Top Business Awards US, the oral-care brand announced on October 26, 2026.

Key Takeaways

  • The selection cited assessments by dental professionals and research on the finished tablet formulation.
  • A 2025 laboratory study compared the tablets with placebo, fluoride toothpaste and untreated enamel.

NOBS toothpaste award and product

Top Business Awards US cited assessments by Dr. Patrick Anghel and Dr. Patrice Smith, as well as the brand’s dental expertise and product design. The award is a selection by the organization, not a clinical finding that the product is superior to all alternatives.

NOBS was co-founded by dentist Dr. Ilon Choai. Its fluoride-free tablets contain 5% nano-hydroxyapatite, along with ingredients including xylitol and zinc citrate. Users chew a tablet before brushing with a wet toothbrush.

What the laboratory study measured

A 2025 study in Dentistry Journal tested the finished NOBS formulation using 120 bovine enamel specimens in a seven-day laboratory model. It compared NOBS tablets with placebo tablets, toothpaste containing 1,100 parts per million fluoride and untreated enamel.

Under those study conditions, NOBS significantly reduced enamel demineralization compared with placebo and untreated enamel. The announcement did not report a result comparing NOBS with the fluoride toothpaste.

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